| 1. | Examples include tetanus toxin and the herpes simplex, rabies, and polio viruses.
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| 2. | Such toxins as the botulinum and tetanus toxins work by targeting the SNARE components.
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| 3. | The tetanus toxin initially binds to peripheral nerve terminals.
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| 4. | Tetanus toxin and botulinum toxin affect neurotransmitter release.
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| 5. | Tetanus toxin causes violent spastic paralysis by blocking the release of ?-aminobutyric acid ( GABA ).
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| 6. | Tetanus toxin is a potent neurotoxin.
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| 7. | In the 1910s he demonstrated that natural and synthetic suprarenin had the ability to neutralize diphtheria and tetanus toxins.
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| 8. | In 1993, Langer's team put the tetanus toxin into microscopic spheres of biodegradable polymer which would release it steadily.
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| 9. | Ricin is several orders of magnitude less toxic than botulinum or tetanus toxin, but the latter are harder to come by.
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| 10. | Tetanus toxin is generated in living bacteria, and is released when the bacteria lyse, such as during spore germination or vegetative growth.
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